Shannen Doherty, best known for her iconic roles in “Beverly Hills, 90210” and “Charmed,” has passed away at 53 after a prolonged battle with breast cancer. Doherty’s publicist, Leslie Sloane, confirmed the sad news in a statement to PEOPLE on Sunday, expressing, “It is with a heavy heart that I confirm the passing of actress Shannen Doherty.”

Shannen Doherty began her acting career as a child, appearing in television series such as “Father Murphy” and “Little House on the Prairie.” She rose to fame in the early ’90s with her role as Brenda Walsh on the hit series “Beverly Hills, 90210.” Doherty’s portrayal of the strong-willed and passionate Brenda made her a household name and a fan favorite. She later starred as Prue Halliwell in the supernatural drama “Charmed,” further cementing her status as a television icon. Throughout her career, Doherty appeared in numerous films and TV shows, demonstrating her versatility and talent as an actress. Despite facing health challenges, she remained a beloved figure in the entertainment industry.